What is Hepatitis C?
Hepatitis C is a virus that attacks the liver. Liver damage typically occurs slowly over 20-30 years and can lead to liver scarring and potentially, to liver cancer or liver failure. It often remains symptomless for many years. The main symptoms if experienced, are fatigue, pain in the liver area, digestive problems and flu-like symptoms. The presence or absence of symptoms is no indication as to how much damage the virus is causing to the liver. This has led hepatitis C to be termed ‘The Silent Killer’.
How Do You Become Infected?
Unlike hepatitis B, there is no vaccine to prevent people from becoming infected. The hepatitis C virus is spread through direct contact with infected blood. The major ways of coming into contact with infected blood are:
• blood transfusions before screening was introduced;
• receiving blood clotting factors for haemophiliacs before heat treatment was introduced;
• sharing equipment for injecting drugs;
• medical or dental interventions in countries where equipment is not adequately sterilised;
• sharing straws, notes etc. for snorting cocaine (cocaine is particularly alkaline and corrosive);
• sharing razors, toothbrushes or other household articles;
• tattooing and body piercing if done using unsterile equipment; and
• a mother infecting a baby at birth.
What are the symptoms of hepatitis C?
Many people who are infected with hepatitis C experience no symptoms at all, making it common that many remain unaware of the disease until they happen to be screened (for example, when donating blood). Others do experience symptoms but mistake them as signs of a cold or flu. The most common symptoms of a new infection of hepatitis C last about 6 months and include:
• fatigue
• anxiety or depression
• tenderness on the right side of the abdomen
• loss of appetite
• jaundice
• nausea and vomiting
• muscle and joint pain
• itching
What happens after you become infected?
Not everyone who is infected by the hepatitis C virus will have chronic hepatitis C. Some individuals will clear the virus from their bodies within six months. Unfortunately, the majority will remain infected unless they can eliminate the virus using treatment.
The damage that chronic hepatitis C does to the body takes time, progressing slowly over many years during this time very few patients have any symptoms. Approximately 20% of patients with chronic hepatitis C will very gradually over 20 or more years develop a condition called cirrhosis (scaring of the liver tissue) resulting in severe damage to the liver and then the above symptoms start to re emerge. Individuals with severely damaged livers are at risk for liver cancer or liver failure. This occurs in 10% of patients.
The virus can be diagnosed by a simple blood test. Doctors also perform additional liver function tests and liver ultrasound scans to determine the extent of liver damage.
How Common is Hepatitis C in Africa?
Country Sample size HCV Prevalence (%) Genotype
Central Africa
Burundi 1184 11.3 4
Cameroon 6015 13.8 4
CAR 709 2.4 4
Chad 290 4.8 4
Congo 4
DRC 2572 5.5 4
Equatorial Guinea 2042 1.7 4
Gabon 1597 9.2 4
Rwanda 610 4.1 4
Sudan 865 2.8 4
Uganda 881 6.6 4
Total 16765 6.0 4
West Africa
Benin 1110 1.6 1-3
Burkina Faso 965 4.9 1-3
Cote d'Ivoire 429 3.3 1-3
Gambia 212 2.4 1-3
Ghana 5033 1.7 1-3
Guinea 2050 5.5 1-3
Mauritania 349 1.1 1-3
Niger 2327 1.8 1-3
Nigeria 669 2.1 1-3
Senegal 352 2.2 1-3
Togo 478 3.9 1-3
Total 13974 2.4 1-3
South and East Africa
Eritrea 323 1.9 1-3
Ethiopia 2080 1.9 1-3
Kenya 1567 0.9 1-3
Madagascar 1564 2.1
Malawi 140 0.7
Mozambique 536 2.8
Somalia 2203 1.5
South Africa 68931 0.1(0.0-3.5) 5
Swaziland 194 1.5
Tanzania 2188 3.2 5
Zambia 583 0.2) 5
Zimbabwe 579 2.0
S & E Africa total 80888 1.6(0.0-8.6) 5
North Africa
Egypt 17.5(13-22) 4
Sudan 3 4
Libya 1.2 4/1
Tunisia 0.55(0.4-0.7) 1b
Algeria 1.8 NA
Mauritania 1.8 NA
Morocco 7.7 1b